IKZF3 / Biotin / 914821

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB8625B (View supplier product page)
Size 0.1 ml
Price $539.00
Antigen IKZF3
Clone 914821
Host Mouse
Isotype IgG1
Conjugate Biotin
Target Species Human
Applications ICFC
Description Aiolos/IKZF3 Antibody (914821) [Biotin]
About IKZF3 and Biotin
IKZF3 This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
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Biotin Excitation and Emission Spectra