CD127 / APC-Fire 810 / A019D5

Product Details
Supplier BioLegend
Catalog #: 351374 (View supplier product page)
Size 100T
Price $457.00
Antigen CD127
Clone A019D5
Host Mouse
Isotype IgG1 κ
Conjugate APC-Fire 810
Target Species Human
Applications FC
Description APC/Fire 810 anti-human CD127 (IL-7Ralpha)
About CD127 and APC-Fire 810
CD127 The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]
APC-Fire 810 APC-Fire™ 810 from BioLegend has an excitation peak at 650nm and an emission peak at 807 nm and is spectrally similar to APC-CF®790. APC-Fire™ 810 is most commonly used in flow cytometry. On a 5-laser Cytek® Aurora, it has very limited spectral spillover into any other channel, so it can be assigned to any antigen with moderate to abundant expression and used in combination with any other fluorophore. This dye is very useful for detecting variably expressed markers, like markers of activation, since it emits so far outside of the autofluorescence range.
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APC-Fire 810 Excitation and Emission Spectra