CD117 / Alk Phosphatase / CBXC-0662

Product Details
Supplier Creative Biolabs
Catalog #: CBMAB-C3106-CQ (View supplier product page)
Size 100 μl
Price $1,000.00
Antigen CD117
Clone CBXC-0662
Host Mouse
Isotype IgG2a
Conjugate Alk Phosphatase
Target Species Human
Applications IF, IHC
Description This product is a mouse antibody that recognizes KIT. The antibody CBXC-0662 can be used for immunoassay techniques such as: IF, IHC.
About CD117 and Alk Phosphatase
CD117 This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene v-kit and is often referred to as proto-oncogene c-Kit. The canonical form of this glycosylated transmembrane protein has an N-terminal extracellular region with five immunoglobulin-like domains, a transmembrane region, and an intracellular tyrosine kinase domain at the C-terminus. Upon activation by its cytokine ligand, stem cell factor (SCF), this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation, differentiation, migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and in mast cell development, migration and function. This protein can be a membrane-bound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2020]
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Alk Phosphatase Excitation and Emission Spectra