Claudin-1 / Alexa Fluor 647 / 421203

Product Details
Supplier Creative Biolabs
Catalog #: CBMAB-C1276-LY (View supplier product page)
Size 100 μg
Price $1,000.00
Antigen Claudin-1
Clone 421203
Host Rat
Isotype IgG2a
Conjugate Alexa Fluor 647
Target Species Human
Applications FC, Microscopy
Description This product is antibody recognizes CLDN1. The antibody 421203 immunoassay techniques such as: FC, CyTOF.
About Claudin-1 and Alexa Fluor 647
Claudin-1 Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra