CBP / DyLight 755 / RW128

Product Details
Supplier Creative Biolabs
Catalog #: CBMAB-K0006-LY (View supplier product page)
Size 200 μl
Price $1,400.00
Antigen CBP
Clone RW128
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 755
Target Species Human, Mouse, Mustelid, Primate, Rat
Applications WB, ICC/IF
Description This product is antibody recognizes CREBBP. The antibody RW128 immunoassay techniques such as: WB, ICC/IF.
About CBP and DyLight 755
CBP This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra