CD163 / PE-Cy5 / GHI/61

Product Details
Supplier BioLegend
Catalog #: 333643 (View supplier product page)
Size 25T
Price $183.00
Antigen CD163
Clone GHI/61
Host Mouse
Isotype IgG1 κ
Conjugate PE-Cy5
Target Species Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description PE/Cyanine5 anti-human CD163
About CD163 and PE-Cy5
CD163 The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
PE-Cy5 PE-Cyanine®5 (PE-Cy5) is a red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy5. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy5. PE-Cy5 has an excitation peak at 496 nm and an emission peak at 667 nm.
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PE-Cy5 Excitation and Emission Spectra