CD45 / Spark NIR 685 / 2D1

Product Details
Supplier Sony
Catalog #: 2442760 (View supplier product page)
Size 100 Tests
Price $382.00
Antigen CD45
Clone 2D1
Host Mouse
Isotype IgG1 κ
Conjugate Spark NIR 685
Target Species Human
Applications FC
Description Spark NIR 685 anti-human CD45
About CD45 and Spark NIR 685
CD45 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Spark NIR 685 Spark NIR® 685 from Biolegend is a fluorophore designed for spectral flow cytometry with an excitation peak at 633 nm and an emission peak at 685 nm. This fluorophore is an alternative to Alexa Fluor™ 660 and can be efficiently excited by the 633 nm laser and can be unmixed from Alexa Fluor™ 647 and Alexa Fluor™ 700.
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Spark NIR 685 Excitation and Emission Spectra