CD85j / APC-Fire 750 / GHI/75

Product Details
Supplier Sony
Catalog #: 2268585 (View supplier product page)
Size 25 Tests
Price $164.00
Antigen CD85j
Clone GHI/75
Host Mouse
Isotype IgG2b κ
Conjugate APC-Fire 750
Target Species Human
Applications FC
Description APC/Fire 750 anti-human CD85j (ILT2)
About CD85j and APC-Fire 750
CD85j This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
APC-Fire 750 APC-Fire™ 750 from Biolegend has an excitation peak at 651 nm and an emission peak at 788 nm and is most commonly used in flow cytometry. Spectrally its similar to APC-Cy7, APC-Alexa 750 and APC-H7
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APC-Fire 750 Excitation and Emission Spectra