CD27 / APC-Fire 750 / LG.3A10

Product Details
Supplier Sony
Catalog #: 1221190 (View supplier product page)
Size 100 μg
Price $382.00
Antigen CD27
Clone LG.3A10
Host Armenian Hamster
Isotype IgG
Conjugate APC-Fire 750
Target Species Human, Mouse, Rat
Applications FC
Description APC/Fire 750 anti-mouse/rat/human CD27
About CD27 and APC-Fire 750
CD27 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
APC-Fire 750 APC-Fire™ 750 from Biolegend has an excitation peak at 651 nm and an emission peak at 788 nm and is most commonly used in flow cytometry. Spectrally its similar to APC-Cy7, APC-Alexa 750 and APC-H7
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APC-Fire 750 Excitation and Emission Spectra