FluoroFinder

	CD45	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
	Spark Blue 550	Spark Blue™ 550 from Biolegend is a fluorophore designed for spectral flow cytometry with an excitation peak at 516 nm and an emission peak at 540 nm. This fluorophore is an alternative to Alexa Fluor™ 532 and can be efficiently excited by the 488 nm laser and can be unmixed from FITC and PE.

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$140.00
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CD45 / Spark Blue 550 / 30-F11