CD86 Monoclonal / Alexa Fluor 647 / IT2.2
CD86 Monoclonal / Alexa Fluor 647 / IT2.2
Product Details
Supplier | Sony | |
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Catalog #: | 2127080 (View supplier product page) | |
Size | 100 Tests | |
Price | $260.00 | |
Antigen | CD86 | |
Clone | IT2.2 | |
Host | Mouse | |
Isotype | IgG2b κ | |
Conjugate | Alexa Fluor 647 | |
Target Species | Human | |
Applications | FC | |
Description | Alexa Fluor 647 anti-human CD86 |
About CD86 and Alexa Fluor 647
CD86 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] | |
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Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |
Citations
Reviews & Ratings
Alexa Fluor 647 Excitation and Emission Spectra
$260.00
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