XPC / Biotin / 6D11
XPC / Biotin / 6D11
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 135447-Biotin-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $681.00 | |
| Antigen | XPC | |
| Clone | 6D11 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | ELISA, WB | |
| Description | XPC (Xeroderma Pigmentosum Group C-complementing Protein, XPCC, DNA Repair Protein Complementing XP-C Cells, p125, RAD4, XP3) (Biotin) Mab 6D11 |
About XPC and Biotin
| XPC | The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017] |
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Citations
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