XPA / APC / 20000
XPA / APC / 20000
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 253484-APC-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $681.00 | |
| Antigen | XPA | |
| Clone | 20000 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | ELISA, IF, WB | |
| Description | XPA (Xeroderma Pigmentosum, Complementation Group A, XP1, XPAC) (APC) Mab 20000 |
About XPA and APC
| XPA | This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
| Additional Sources |
|
|---|
