FluoroFinder

	Supplier	US Biological
	Catalog #:	253463-APC-100UL (View supplier product page)
	Size	100 μl
	Price	$681.00
	Antigen	WRN
	Clone	2F7
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	APC
	Target Species	Human
	Applications	ELISA, WB
	Description	WRN (Werner Syndrome, DKFZp686C2056, RECQ3, RECQL2, RECQL3) (APC) Mab 2F7

	WRN	This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017]
	APC	Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

	Additional Sources

WRN / APC / 2F7