WRN / Biotin /
WRN / Biotin /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 043897-Biotin-200UL (View supplier product page) | |
| Size | 200 μl | |
| Price | $711.00 | |
| Antigen | WRN | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | ELISA, WB | |
| Description | WRN, ID (T802) (WRN, RECQ3, RECQL2, Werner syndrome ATP-dependent helicase, DNA helicase, RecQ-like type 3, Exonuclease WRN, RecQ protein-like 2) (Biotin) Pab |
About WRN and Biotin
| WRN | This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017] |
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Citations
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