RNF216 / Biotin /
RNF216 / Biotin /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | T8319-05B-Biotin-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $736.00 | |
| Antigen | RNF216 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Mouse | |
| Applications | WB | |
| Description | TRIAD3A (E3 Ubiquitin Ligase TRIAD3A, E3 ubiquitin-protein ligase RNF216, RING finger protein 216, Ubiquitin-conjugating enzyme 7-interacting protein 1, UbcM4-interacting protein 83, Triad domain-containing protein 3, Rnf216, Triad3, Ubce7ip1, Uip83, Zin) (Biotin) Pab |
About RNF216 and Biotin
| RNF216 | This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008] |
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Citations
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