RNF216 / Biotin /
RNF216 / Biotin /
Product Details
Supplier | US Biological | |
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Catalog #: | T8319-04A-Biotin-200UL (View supplier product page) | |
Size | 200 μl | |
Price | $711.00 | |
Antigen | RNF216 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Biotin | |
Target Species | Human | |
Applications | ELISA, IHC, WB | |
Description | TRIAD3, CT (E3 Ubiquitin-protein Ligase RNF216, RING Finger Protein 216, Ubiquitin Conjugating Enzyme 7 Interacting Protein 1, Triad3 Protein, Zinc Finger Protein Inhibiting NF-kappa-B, Triad Domain-containing Protein 3, UBCE7IP1, RNF216, ZIN) (Biotin) Pab |
About RNF216 and Biotin
RNF216 | This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008] |
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