CD27 / MaxLight 490 / 1E2-A3

Product Details
Supplier US Biological
Catalog #: 124595-ML490-100UL (View supplier product page)
Size 100 μl
Price $681.00
Antigen CD27
Clone 1E2-A3
Host Mouse
Isotype IgG2b
Conjugate MaxLight 490
Target Species Human
Applications FC, IP, WB
Description CD27 (CD27 Antigen, CD27L Receptor, T-cell Activation Antigen CD27, T14, TNFRSF7, Tumor Necrosis Factor Receptor Superfamily Member 7) (MaxLight 490) Mab 1E2-A3
About CD27 and MaxLight 490
CD27 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
MaxLight 490 MaxLight 490 is excited by the 488 laser and emission captured by the 515/30 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.
Citations
Additional
Sources
Reviews & Ratings
MaxLight 490 Excitation and Emission Spectra