CD27 / MaxLight 490 / 1E2-A3
CD27 / MaxLight 490 / 1E2-A3
Product Details
Supplier | US Biological | |
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Catalog #: | 124595-ML490-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $681.00 | |
Antigen | CD27 | |
Clone | 1E2-A3 | |
Host | Mouse | |
Isotype | IgG2b | |
Conjugate | MaxLight 490 | |
Target Species | Human | |
Applications | FC, IP, WB | |
Description | CD27 (CD27 Antigen, CD27L Receptor, T-cell Activation Antigen CD27, T14, TNFRSF7, Tumor Necrosis Factor Receptor Superfamily Member 7) (MaxLight 490) Mab 1E2-A3 |
About CD27 and MaxLight 490
CD27 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] | |
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MaxLight 490 | MaxLight 490 is excited by the 488 laser and emission captured by the 515/30 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |