CD357 / PE / 2H4
CD357 / PE / 2H4
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 252823-PE-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $681.00 | |
| Antigen | CD357 | |
| Clone | 2H4 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | PE | |
| Target Species | Human | |
| Applications | ELISA, WB | |
| Description | TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18, AITR, GITR, GITR-D) (PE) Mab 2H4 |
About CD357 and PE
| CD357 | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Citations
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