CD137 Monoclonal / PE / 17B5-1H1

Product Details
Supplier Miltenyi Biotec
Catalog #: 130-102-568 (View supplier product page)
Size 30 μg in 1 ml
Price $70.00
Antigen CD137
Clone 17B5-1H1
Host Hamster
Isotype IgG2
Conjugate PE
Target Species Mouse
Applications FC, Functional
Description Clone 17B5-1H1 reacts with mouse CD137, also known as 4-1BB or TNFRSF9, a member of the TNFR superfamily. It is expressed on the cell surface of T cells upon activation. The interaction of CD137 with its ligand, 4-1BBL, on antigen presenting cells (APCs) delivers a bidirectional costimulatory signal. CD137 engagement is shown to be required for CD8+ T cell survival and memory formation. The monoclonal antibody 17B5 is reported to have strong antagonistic effect in in vitro functional assays.
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PE Excitation and Emission Spectra