FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-099-595 (View supplier product page)
	Size	30 Tests in 300 μl
	Price	$128.00
	Antigen	HLA Class I B8
	Clone	REA145
	Host	cell line
	Isotype	IgG1
	Conjugate	APC
	Target Species	Human
	Applications	FC
	Description	Clone REA145 recognizes HLA B8, a class I human leukocyte antigen (HLA). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of three domains, of which one comprises the peptide binding groove. Antigens binding to class I molecules are 8–10 amino acids long and play an important role in recognition of the virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells. \| Additional information: Clone REA145 displays negligible binding to Fc receptors.

$128.00
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HLA Class I B8 Monoclonal / APC / REA145