SSR2 / FITC / 4C1

Product Details
Supplier US Biological
Catalog #: 133873-FITC-100UL (View supplier product page)
Size 100 μl
Price $681.00
Antigen SSR2
Clone 4C1
Host Mouse
Isotype IgG2a κ
Conjugate FITC
Target Species Human
Applications ELISA, WB
Description SSR2 (TRAPB, Translocon-associated Protein Subunit beta, Signal Sequence Receptor Subunit beta, SSR-beta, DKFZp686F19123, HSD25) (FITC) Mab 4C1
About SSR2 and FITC
SSR2 The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008]
FITC Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.
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FITC Excitation and Emission Spectra