CD131 Monoclonal / Biotin / REA193

Citations: (2)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-101-935 (View supplier product page)
Size 30 μg in 1 ml
Price $60.00
Antigen CD131
Clone REA193
Host Human
Isotype IgG1
Conjugate Biotin
Target Species Mouse
Applications FC
Description Clone REA193 recognizes CD131, the IL-3 receptor β subunit. CD131 is a single-pass type I transmembrane protein, belongs to the cytokine receptor superfamily, and is shared by IL-3, IL-5, and GM-CSF receptors. The receptor-specific α subunits is mainly involved in ligand binding and the common β subunit, CD131, is important for transducing the signal initiated by binding of the ligands to respective receptors. | Additional information: Clone REA193 displays negligible binding to Fc receptors. |
About CD131 and Biotin
CD131 The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]
Citations
PMID 8466757
PMID 9766809
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Biotin Excitation and Emission Spectra