FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-103-348 (View supplier product page)
	Size	9 μg in 300 μl
	Price	$55.00
	Antigen	CD124
	Clone	REA235
	Host	recombinant human
	Isotype	IgG1
	Conjugate	APC
	Target Species	Mouse
	Applications	FC
	Description	Identification and enumeration of CD124 (IL-4Rα)+ cells by flow cytometry

	CD124	This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
	APC	Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

$55.00
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CD124 Monoclonal / APC / REA235