FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-104-477 (View supplier product page)
	Size	30 μg in 1 ml
	Price	$160.00
	Antigen	CD83
	Clone	REA304
	Host	Human
	Isotype	IgG1
	Conjugate	APC-Vio770
	Target Species	Mouse
	Applications	FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
	Description	Clone REA304 recognizes the mouse CD83 antigen, a Single-pass type I membrane protein which belongs to the immunoglobulin superfamily. Murine CD83 is moderately expressed on resting T cells and DC, but strongly increases in its expression on T cells following activation with antigenic peptides or T cell receptor-specific monoclonal antibody. When returning to the resting state, T cells down-regulate CD83 again. Histological analysis of serial spleen sections revealed a CD83 expression pattern resembling that of MIDC-8, a known murine DC marker molecule. \| Additional information: Clone REA304 displays negligible binding to Fc receptors.

	CD83	The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
	APC-Vio770	APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.

$160.00
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CD83 Monoclonal / APC-Vio770 / REA304