Mannose Receptor Monoclonal / APC / DCN228
Mannose Receptor Monoclonal / APC / DCN228
Citations:
(8)
Product Details
| Supplier | Miltenyi Biotec | |
|---|---|---|
| Catalog #: | 130-099-731 (View supplier product page) | |
| Size | 30 Tests in 300 μl | |
| Price | $128.00 | |
| Antigen | Mannose Receptor | |
| Clone | DCN228 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | MICS (MACSima Imaging Cyclic Staining), FC, IF, IHC | |
| Description | The mannose receptor (MR), also known as macrophage MR or CD206, is a 162–175 kDa type I membrane protein. It contains an N-terminal cystein-rich domain and eight C-type lectin-like domains (CTLDs), beside a transmembrane and a cytoplasmic domain. CD206 is expressed by macrophages, dendritic cells, and subsets of endothelial cells, but not on monocytes. The MR recognizes multiple mainly microbial carbohydrates with mannose, fucose, or N-acetyl glucosamine residues. The MR mediates endocytosis and phagocytosis, linked to antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. |
Citations
| PMID 2258707 | ||
|---|---|---|
| PMID 2914913 | ||
| PMID 3458213 | ||
| PMID 7629501 | ||
| PMID 10779515 | ||
| PMID 15878980 | ||
| PMID 16203868 | ||
| PMID 22213010 | ||
| Additional Sources |
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Reviews & Ratings
APC Excitation and Emission Spectra
$128.00
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