CD300e Monoclonal / Biotin / UP-H2

Citations: (2)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-101-836 (View supplier product page)
Size 30 tests in 300 µL
Price $100.00
Antigen CD300e
Clone UP-H2
Host Mouse
Isotype IgG1,κappa
Conjugate Biotin
Target Species Human
Applications FC
Description The monoclonal antibody UP-H2 reacts with human CD300e, also known as IREM-2, LMIR6, or CMRF35-A5. This 34 kDa activating receptor of the immunglobulin superfamily is expressed on mature myeloid dendritic cells and monocytes and is down-regulated on immature dendritic cells. CD300e interacts with DAP-12, which mediates acivating signals. It is reported that the alloreactive response of naive T cells is enhanced by IREM-2 activation of mDCs.
About CD300e and Biotin
CD300e This gene encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells. The protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an activating receptor. [provided by RefSeq, Nov 2012]
Citations
PMID 15557162
PMID 20039296
Additional
Sources
Reviews & Ratings
Biotin Excitation and Emission Spectra