CD300e Monoclonal / Biotin / UP-H2
CD300e Monoclonal / Biotin / UP-H2
Citations:
(2)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-101-836 (View supplier product page) | |
Size | 30 tests in 300 µL | |
Price | $100.00 | |
Antigen | CD300e | |
Clone | UP-H2 | |
Host | Mouse | |
Isotype | IgG1,κappa | |
Conjugate | Biotin | |
Target Species | Human | |
Applications | FC | |
Description | The monoclonal antibody UP-H2 reacts with human CD300e, also known as IREM-2, LMIR6, or CMRF35-A5. This 34 kDa activating receptor of the immunglobulin superfamily is expressed on mature myeloid dendritic cells and monocytes and is down-regulated on immature dendritic cells. CD300e interacts with DAP-12, which mediates acivating signals. It is reported that the alloreactive response of naive T cells is enhanced by IREM-2 activation of mDCs. |
About CD300e and Biotin
CD300e | This gene encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells. The protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an activating receptor. [provided by RefSeq, Nov 2012] |
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Citations
PMID 15557162 | ||
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PMID 20039296 | ||
Additional Sources |
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Reviews & Ratings
Biotin Excitation and Emission Spectra
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