CD71 Monoclonal / APC-Vio770 / AC102

Citations: (4)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-104-152 (View supplier product page)
Size 30 tests in 300 µL
Price $151.00
Antigen CD71
Clone AC102
Host Mouse
Isotype IgG2a κ
Conjugate APC-Vio770
Target Species Human
Applications FC
Description The CD71 antibody recognizes the transferrin receptor, which is essential for iron transport into proliferating cells. CD71 is expressed on marrow stromal cells (MSCs) from bone marrow, on activated T and B lymphocytes, macrophages, and all proliferating cells. It is upregulated on lymphocytes during proliferative responses to antigens or mitogens but is not expressed on resting lymphocytes. CD71 is present on reticulocytes and erythroid progenitors in fetal liver, cord blood, and peripheral blood, yet it is lost as these differentiate to mature erythrocytes.
About CD71 and APC-Vio770
CD71 This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
APC-Vio770 APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.
Citations
Reviews & Ratings
APC-Vio770 Excitation and Emission Spectra