MICA/MICB Monoclonal / PE / 6D4

Citations: (1)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-100-889 (View supplier product page)
Size 30 tests in 300 µL
Price $125.00
Antigen MICA/MICB
Clone 6D4
Host Mouse
Isotype IgG2a κ
Conjugate PE
Target Species Human
Applications FC
Description The monoclonal antibody 6D4 recognizes MICA and MICB, which are transmembrane glycoproteins related to major histocompatibility complex (MHC) class I molecules. In contrast to other MHC class I proteins, MICA/B have no association with β2-microglobulin and do not bind peptides. They are ligands for NKG2D, which is expressed on NK cells and many T cells. MICA/B are expressed on endothelial cells and fibroblasts and are stress-induced in epithelial cells.
Citations
PMID 2007850
PMID 10367903
PMID 10426993
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PE Excitation and Emission Spectra