CD2 Monoclonal / APC / LT2

Citations: (1)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-098-579 (View supplier product page)
Size 100 Tests in 1 ml
Price $330.00
Antigen CD2
Clone LT2
Host Mouse
Isotype IgG2b κ
Conjugate APC
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Functional
Description The CD2 antibody recognizes the human CD2 antigen, a 50 kDa single-chain transmembrane glycoprotein also known as LFA-2 or receptor for sheep erythrocytes. CD2 belongs to the Ig superfamily and is involved in cell signaling and lymphocyte adhesion. The CD2 antibody reacts with 80–90% of peripheral blood lymphocytes and more than 95% of thymocytes. The antibody recognizes all T cells and a subset of natural killer (NK) cells.
About CD2 and APC
CD2 The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Citations
PMID 9379483
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APC Excitation and Emission Spectra