FluoroFinder

	Supplier	US Biological
	Catalog #:	G9039-53A-PE-200UL (View supplier product page)
	Size	200 μl
	Price	$711.00
	Antigen	RASGRF1
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	PE
	Target Species	Human
	Applications	ELISA, IHC, WB
	Description	RASGRF1 (S929) (Ras-specific Guanine Nucleotide-releasing Factor 1, Ras-GRF1, Guanine Nucleotide-releasing Protein, Ras-specific Nucleotide Exchange Factor CDC25, CDC25, GNRP, GRF1) (PE) Pab

	RASGRF1	The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
	PE	Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

	Additional Sources

RASGRF1 / PE /