Rab3B / FITC / 3F12
Rab3B / FITC / 3F12
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 132205-FITC-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $681.00 | |
| Antigen | Rab3B | |
| Clone | 3F12 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | FITC | |
| Target Species | Human | |
| Applications | ELISA, IF, IHC, WB | |
| Description | RAB3B (Ras-related Protein Rab-3B) (FITC) Mab 3F12 |
About Rab3B and FITC
| Rab3B | Enables GDP binding activity; GTPase activity; and myosin V binding activity. Involved in several processes, including positive regulation of dopamine uptake involved in synaptic transmission; regulation of synaptic vesicle cycle; and regulation of vesicle size. Located in perinuclear region of cytoplasm and vesicle. Is active in dopaminergic synapse. Is anchored component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022] | |
|---|---|---|
| FITC | Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark. |
Citations
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