CD5 Monoclonal / Vio Blue / 53-7.3

Citations: (2)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-102-460 (View supplier product page)
Size 30 μg in 1 ml
Price $140.00
Antigen CD5
Clone 53-7.3
Host Rat
Isotype IgG2a κ
Conjugate Vio Blue
Target Species Mouse
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Description CD5, which is recognized by the monoclonal antibody 53-7.3, is a 67 kDa protein also known as Ly-1. It is expressed by a majority of thymocytes, mature T cells, and a subset of B cells. The expression of CD5 by a small B cell subset characterizes a developmentally and functionally distinct lineage of B cells called B-1a cells. CD5 plays a role in the interaction of T and B cells and is a counter-receptor for CD72.
About CD5 and Vio Blue
CD5 This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
Vio Blue Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec).
Citations
PMID 398327
PMID 7542801
Additional
Sources
Reviews & Ratings
Vio Blue Excitation and Emission Spectra