CD5 Monoclonal / Vio Blue / 53-7.3
CD5 Monoclonal / Vio Blue / 53-7.3
Citations:
(2)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-102-460 (View supplier product page) | |
Size | 30 μg in 1 ml | |
Price | $140.00 | |
Antigen | CD5 | |
Clone | 53-7.3 | |
Host | Rat | |
Isotype | IgG2a κ | |
Conjugate | Vio Blue | |
Target Species | Mouse | |
Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC | |
Description | CD5, which is recognized by the monoclonal antibody 53-7.3, is a 67 kDa protein also known as Ly-1. It is expressed by a majority of thymocytes, mature T cells, and a subset of B cells. The expression of CD5 by a small B cell subset characterizes a developmentally and functionally distinct lineage of B cells called B-1a cells. CD5 plays a role in the interaction of T and B cells and is a counter-receptor for CD72. |
About CD5 and Vio Blue
CD5 | This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016] | |
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Vio Blue | Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec). |
Citations
PMID 398327 | ||
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PMID 7542801 | ||
Additional Sources |
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Reviews & Ratings
Vio Blue Excitation and Emission Spectra
$140.00
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