CD23 Monoclonal / APC / B3B4

Citations: (2)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-102-577 (View supplier product page)
Size 30 μg in 1 ml
Price $90.00
Antigen CD23
Clone B3B4
Host Rat
Isotype IgG2a κ
Conjugate APC
Target Species Mouse
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Description The monoclonal antibody B3B4 recognizes CD23, also known as low affinity IgE Fc receptor (FcεRII), a type II integral membrane glycoprotein. CD23 is expressed on mature B cells, but not on CD5+ B-1 cells, activated B cells, follicular dendritic cells of immunized mice and on a subset of splenic dendritic cells. Clone B3B4 is reported to block IgE binding to FcεRII.
About CD23 and APC
CD23 The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Citations
Reviews & Ratings
APC Excitation and Emission Spectra