CD23 Monoclonal / APC / B3B4
CD23 Monoclonal / APC / B3B4
Citations:
(2)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-102-577 (View supplier product page) | |
Size | 30 μg in 1 ml | |
Price | $90.00 | |
Antigen | CD23 | |
Clone | B3B4 | |
Host | Rat | |
Isotype | IgG2a κ | |
Conjugate | APC | |
Target Species | Mouse | |
Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC | |
Description | The monoclonal antibody B3B4 recognizes CD23, also known as low affinity IgE Fc receptor (FcεRII), a type II integral membrane glycoprotein. CD23 is expressed on mature B cells, but not on CD5+ B-1 cells, activated B cells, follicular dendritic cells of immunized mice and on a subset of splenic dendritic cells. Clone B3B4 is reported to block IgE binding to FcεRII. |
About CD23 and APC
CD23 | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] | |
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APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
PMID 1532811 | ||
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PMID 2950171 | ||
PMID 9316637 | ||
Additional Sources |
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Reviews & Ratings
APC Excitation and Emission Spectra
$90.00
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