CD111 / MaxLight 550 /
CD111 / MaxLight 550 /
Product Details
Supplier | US Biological | |
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Catalog #: | 212933-ML550-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $865.00 | |
Antigen | CD111 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | MaxLight 550 | |
Target Species | Human | |
Applications | IHC, WB | |
Description | PVRL1 (Poliovirus Receptor-related 1, ED4, PRR, HIgR, HVEC, OFC7, PRR1, PVRR, CD111, PVRR1, SK-12, CLPED1, Nectin-1) (MaxLight 550) Pab |
About CD111 and MaxLight 550
CD111 | This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009] | |
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MaxLight 550 | MaxLight 550 is excited by the 561 laser and emission captured by the 585/42 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |