CD141 / PE-Vio770 / AD5-14H12

Product Details
Supplier Miltenyi Biotec
Catalog #: 130-100-218 (View supplier product page)
Size 30 Tests
Price $138.00
Antigen CD141
Clone AD5-14H12
Host Mouse
Isotype IgG1 κ
Conjugate PE-Vio770
Target Species Human
Applications FC
Description Detection of human CD141 (BDCA-3)+ type-2 myeloid dendritic cells (MDC2s)
About CD141 and PE-Vio770
CD141 The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]
PE-Vio770 PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
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PE-Vio770 Excitation and Emission Spectra