p53 / MaxLight 650 /

Product Details
Supplier US Biological
Catalog #: 138238-ML650-100UL (View supplier product page)
Size 100 μl
Price $742.00
Antigen p53
Clone
Host Rabbit
Isotype IgG
Conjugate MaxLight 650
Target Species Human
Applications WB
Description PRAC (Small Nuclear Protein PRAC, Prostate, Rectum and Colon Expressed Gene pro, C17orf92, MGC32520) (MaxLight 650) Pab
About p53 and MaxLight 650
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
MaxLight 650 MaxLight 650 is excited by the 640 laser and emission captured by the 670/30 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.
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MaxLight 650 Excitation and Emission Spectra