CD49a Monoclonal / Biotin / TS2/7

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-101-401 (View supplier product page)
Size 100 Tests in 1 ml
Price $270.00
Antigen CD49a
Clone TS2/7
Host Mouse
Isotype IgG1,κappa
Conjugate Biotin
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Description Clone TS2/7 recognizes the cell adhesion molecule human CD49a, which is a 200 kDa heterodimeric integrin receptor. CD49a, also known as integrin α1, interacts with integrin β1 (CD29) to form the VLA-1 complex which functions as a receptor for collagen and laminin-1. Integrin α1 plays a role in cell-cell adhesion and T cell proliferation and is expressed by activated T cells, NK cells, neuronal cells, fibroblasts, and mesenchymal cells.
About CD49a and Biotin
CD49a This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]
Citations
PMID 2415516
PMID 7682756
PMID 15676216
Additional
Sources
Reviews & Ratings
Submit a Review

Biotin Excitation and Emission Spectra