Perforin Monoclonal / Vio Blue / delta G9

Product Details
Supplier Miltenyi Biotec
Catalog #: 130-099-952 (View supplier product page)
Size 30 Tests
Price $126.00
Antigen Perforin
Clone delta G9
Host Mouse
Isotype IgG2b κ
Conjugate Vio Blue
Target Species Human
Applications FC
Description Identification and enumeration of perforin-producing cells, e.g., T and NK cells
About Perforin and Vio Blue
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
Vio Blue Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec).
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Vio Blue Excitation and Emission Spectra