CD86 Monoclonal / PE-Vio770 / FM95

Product Details
Supplier Miltenyi Biotec
Catalog #: 130-098-214 (View supplier product page)
Size 100 Tests
Price $296.00
Antigen CD86
Clone FM95
Host Mouse
Isotype IgG1 κ
Conjugate PE-Vio770
Target Species Human, Non-Human Primate
Applications FC
Description Detection of CD86+ monocytes, monitoring of DC maturation
About CD86 and PE-Vio770
CD86 This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
PE-Vio770 PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
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PE-Vio770 Excitation and Emission Spectra