CD16 Monoclonal / Vio Blue / VEP13
CD16 Monoclonal / Vio Blue / VEP13
Citations:
(11)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-099-080 (View supplier product page) | |
Size | 100 Tests in 1 ml | |
Price | $345.00 | |
Antigen | CD16 | |
Clone | VEP13 | |
Host | Mouse | |
Isotype | IgM κ | |
Conjugate | Vio Blue | |
Target Species | Human | |
Applications | FC | |
Description | CD16 is a 50–80 kDa glycoprotein that is expressed in two different isoforms. The transmembrane form is found on human NK cells, macrophages, and mast cells, while the glycosylphosphatidylinositol (GPI)-linked form is present on neutrophils. | The human CD16 antigen is a low-affinity receptor for aggregated IgG. The transmembrane form plays a role in signal transduction, NK cell activation, and antibody-dependent cellular cytotoxicity. Clone VEP13 recognizes both the extracellular domain of the transmembrane form as well as the GPI-linked form of the human CD16 antigen. CD16 is expressed on the majority of rhesus monkey NK cells and on a subset of monocytes but not on granulocytes. |
Citations
PMID 18431484 | ||
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Additional Sources |
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Reviews & Ratings
Vio Blue Excitation and Emission Spectra
$345.00
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