CD16 Monoclonal / Vio Blue / VEP13

Citations: (11)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-099-080 (View supplier product page)
Size 100 Tests in 1 ml
Price $345.00
Antigen CD16
Clone VEP13
Host Mouse
Isotype IgM κ
Conjugate Vio Blue
Target Species Human
Applications FC
Description CD16 is a 50–80 kDa glycoprotein that is expressed in two different isoforms. The transmembrane form is found on human NK cells, macrophages, and mast cells, while the glycosylphosphatidylinositol (GPI)-linked form is present on neutrophils. | The human CD16 antigen is a low-affinity receptor for aggregated IgG. The transmembrane form plays a role in signal transduction, NK cell activation, and antibody-dependent cellular cytotoxicity. Clone VEP13 recognizes both the extracellular domain of the transmembrane form as well as the GPI-linked form of the human CD16 antigen. CD16 is expressed on the majority of rhesus monkey NK cells and on a subset of monocytes but not on granulocytes.
Citations
PMID 18431484
Additional
Sources
Reviews & Ratings
Vio Blue Excitation and Emission Spectra