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Urokinase MaxLight 405 (3B8, Mouse) - Reactivity: Human
Product Details
| Description | Urokinase (Urokinase-type Plasminogen Activator, U-plasminogen Activator, uPA, PLAU) (MaxLight 405) Mab 3B8 | |
|---|---|---|
| Conjugate | MaxLight 405 | |
| Clone | 3B8 | |
| Target Species | Human | |
| Applications | WB, ELISA | |
| Supplier | US Biological | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Urokinase
This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
About MaxLight 405
MaxLight 405 is excited by the 405 laser and emission captured by the 450/50 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.
MaxLight 405 is excited by the 405 laser and emission captured by the 450/50 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.
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