FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-102-191 (View supplier product page)
	Size	30 μg in 1 ml
	Price	$50.00
	Antigen	CD107a
	Clone	1D4B
	Host	Rat
	Isotype	IgG2a κ
	Conjugate	FITC
	Target Species	Mouse
	Applications	MICS (MACSima Imaging Cyclic Staining), IF, IHC, FC
	Description	The monoclonal antibody 1D4B recognizes mouse CD107a, a 110-140 kDa type I membrane protein which is heavily glycosylated from a 40 kDa core protein. CD107a, also known as LAMP-1 (lysosome-associated membrane protein 1) is a ligand for galaptin, an S-type lectin, and is located on lysosomal membrans that can be used to distinguish lysosomes from other organelles. It is expressed on epithelial cells, macrophages, and on cells of different organs in mice.

	CD107a	The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]
	FITC	Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.

$50.00
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CD107a Monoclonal / FITC / 1D4B