PI3K C2 beta / HRP / 300000
PI3K C2 beta / HRP / 300000
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 131338-HRP-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $681.00 | |
| Antigen | PI3K C2 beta | |
| Clone | 300000 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | HRP | |
| Target Species | Human | |
| Applications | ELISA, WB | |
| Description | PIK3C2B (Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Subunit beta, PI3K-C2-beta, Phosphoinositide 3-kinase-C2-beta, PIK3C2B, PtdIns-3-kinase C2 Subunit beta, C2-PI3K, DKFZp686G16234) (HRP) Mab 3E5 |
About PI3K C2 beta and HRP
| PI3K C2 beta | The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008] |
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Citations
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