CD49b Monoclonal / APC-Vio770 / DX5

Product Details
Supplier Miltenyi Biotec
Catalog #: 130-105-291 (View supplier product page)
Size 9 μg in 30 μl
Price $60.00
Antigen CD49b
Clone DX5
Host Rat
Isotype IgM κ
Conjugate APC-Vio770
Target Species Mouse
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Description Clone DX5 recognizes the mouse CD49b antigen, also known as α2 integrin or very late antigen-2, which is expressed on the vast majority of mouse natural killer (NK) cells and on a subset of NKT cells. CD49b is not as mouse strain-restricted as other NK cell markers, for example, NK1.1, and is expressed by most common inbred mouse strains.
About CD49b and APC-Vio770
CD49b This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
APC-Vio770 APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

APC-Vio770 Excitation and Emission Spectra