CD2 Monoclonal / Biotin / RM2-5

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-101-963 (View supplier product page)
Size 30 μg in 1 ml
Price $60.00
Antigen CD2
Clone RM2-5
Host Rat
Isotype IgG2b λ
Conjugate Biotin
Target Species Mouse
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Functional
Description The monoclonal antibody RM2-5 recognizes the type I transmembrane glycoprotein CD2, also known as LFA-2 or Ly-37. In mouse, CD2 is expressed on all lymphocytes except a subpopulation of intraepithelial T lymphocytes. It is a major receptor for CD48 and is involved in activation and differentiation of T cells. CD2-mediated cell-cell adhesion can be blocked by the RM2-5 antibody.
About CD2 and Biotin
CD2 The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016]
Citations
PMID 1700989
PMID 2463634
PMID 8871350
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Biotin Excitation and Emission Spectra