FluoroFinder

	Supplier	US Biological
	Catalog #:	P3140-01-FITC-100UL (View supplier product page)
	Size	100 μl
	Price	$801.00
	Antigen	Serpin F1
	Clone	2Q1840, 10F12.2
	Host	Mouse
	Isotype	IgG2a
	Conjugate	FITC
	Target Species	Human
	Applications	ELISA, IHC, WB
	Description	PEDF (Pigment Epithelial Derived Factor) (FITC) Mab 2Q1840, 10F12.2

	Serpin F1	This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016]
	FITC	Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.

	Additional Sources

Serpin F1 / FITC / 2Q1840, 10F12.2