PCNA / Biotin / SPM350
PCNA / Biotin / SPM350
Product Details
Supplier | US Biological | |
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Catalog #: | 172137-AF-Biotin-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $694.00 | |
Antigen | PCNA | |
Clone | SPM350 | |
Host | Mouse | |
Isotype | IgG2a κ | |
Conjugate | Biotin | |
Target Species | Rat | |
Applications | ELISA, IF, IHC, IP, WB | |
Description | PCNA (Cyclin, DNA polymerase delta auxiliary Protein, Mutagen-sensitive 209 Protein, PCNAR, Polymerase delta accessory Protein) (Biotin) Mab SPM350 |
About PCNA and Biotin
PCNA | The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008] |
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