Pappalysin-1 / MaxLight 650 / 1G3
Pappalysin-1 / MaxLight 650 / 1G3
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 130864-ML650-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $681.00 | |
| Antigen | Pappalysin-1 | |
| Clone | 1G3 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | MaxLight 650 | |
| Target Species | Human | |
| Applications | FC, WB | |
| Description | PAPPA (Pappalysin-1, Insulin-like Growth Factor-dependent IGF-binding Protein 4 Protease, IGF-dependent IGFBP-4 Protease, IGFBP-4ase, Pregnancy-associated Plasma Protein A, PAPP-A) (MaxLight 650) Mab 1G3 |
About Pappalysin-1 and MaxLight 650
| Pappalysin-1 | This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| MaxLight 650 | MaxLight 650 is excited by the 640 laser and emission captured by the 670/30 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |
Citations
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