p53 / MaxLight 405 / 9L526

Product Details
Supplier US Biological
Catalog #: P1001-30E-ML405-100UL (View supplier product page)
Size 100 μl
Price $628.00
Antigen p53
Clone 9L526
Host Mouse
Isotype IgG1 κ
Conjugate MaxLight 405
Target Species Human
Applications ELISA
Description p53 (Tumor Suppressor Protein, Oncogene Protein) (MaxLight 405) Mab 9L526
About p53 and MaxLight 405
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
MaxLight 405 MaxLight 405 is excited by the 405 laser and emission captured by the 450/50 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.
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MaxLight 405 Excitation and Emission Spectra